De novo assembly of genomes and metagenomes from next generation sequencing data

Project ID
FG-128
Project Categories
Life Science
NSF Grant Number
DBI-0845685
NSF Grant URL
http://www.nsf.gov/awardsearch/showAward.do?AwardNumber=0845685
Completed
Abstract
We will use the FutureGrid computing resource to assemble next-generation sequencing (NGS) reads from eukaryotic genome projects and metagenome project, including the human microbiome project and the earth microbiome project. The massive sequencing data generated by NGS sequencers have revolutionized many fields of biology, but requires extensive computing resources to be analyzed. In particular, we would like to utilize the computer clusters with large continuous RAM from the FutureGird project to test some assembly algorithms we developed for NGS data and to analyze large datasets from microbiome projects that may lead to new findings.
Use of FutureSystems
We will run the assembly algorithms we developed on large datasets from microbiome projects.
Scale of Use
We need to use computer nodes with large RAM for a week.