Targeted Genome Mining of Natural Products

Project ID
FG-490
Project Categories
Life Science
Project Keywords
Completed
Abstract
In this proposal we will develop strategies to mine the chemical diversity encoded in filamentous fungi, discover the enzymes that give rise to the structural complexity and engineer enzymes into useful biocatalysts where applicable. We will develop and validate a target-guided mining approach that connects genomics-based mining to clinically relevant biological activity.
Use of FutureSystems
We will be performing large scale genome assemblies, annotations, transcriptomics analysis that are memory intensive. We will require storage space for databases downloaded from publicly available repositories.
Scale of Use
I want to run a set of analysis on all databases and for each I'll need at least three days to do that.